Cariprazine as a treatment for negative psychotic symptoms in first-episode psychosis: case series.
Affiliation
King's College London; South London and Maudsley NHS Foundation Trust; Southampton University; Coventry and Warwickshire Partnership NHS Trust;Publication date
2022-04-28
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Negative psychotic symptoms are among the most disabling features of schizophrenia, and are strongly associated with relatively poor clinical and functional outcomes. However, there are no effective treatments for negative symptoms, and this represents a major unmet clinical need. Recent research has shown that negative symptoms are already present in many patients at illness onset. There is evidence that cariprazine may improve negative symptoms in patients with chronic schizophrenia. However, its utility in treating negative symptoms in the early stage of the disorder is unclear. Here, we report six cases of patients with first-episode psychosis who were treated with cariprazine.Citation
Demjaha A, Iacoponi E, Hansen L, Peddu P, McGuire P. Cariprazine as a treatment for negative psychotic symptoms in first-episode psychosis: case series. BJPsych Open. 2022 Apr 28;8(3):e88. doi: 10.1192/bjo.2022.56.Type
ArticleAdditional Links
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059739/#:~:text=There%20is%20evidence%20that%20cariprazine,who%20were%20treated%20with%20cariprazine.PMID
35481438Journal
BJPsych OpenPublisher
Cambridge University Pressae974a485f413a2113503eed53cd6c53
10.1192/bjo.2022.56