Impact of thermo-mechanical skin treatment on refraction and keratometry in patients with dry eye disease and the implications for cataract surgery
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Author
Blanco-Vázquez, MartaGil-Cazorla, Raquel
Barua, Ankur
Taneja, Mukesh
Hanneken, Ludger
Shah, Sunil
Affiliation
University of Valladolid; Aston University; Sandwell and West Birmingham NHS Trust; Khmer Sight Foundation; et al.Publication date
2024-04-08Subject
Ophthalmology
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Purpose: To determine the changes in keratometry measurements and refraction in patients having the thermo-mechanical periorbital skin treatment, Tixel®, to treat dry eye disease (DED). Methods: A multi-centre, prospective, non-masked study was conducted. DED patients were recruited in 3 international centres and were evaluated in 5 visits separated by an interval of 2 weeks except for the last visit which took place after 18 weeks from visit 1. The same clinical examination was performed at all visits: OSDI questionnaire, tear stability, keratometry, best corrected visual acuity and refraction. Tixel® treatment was applied at the first 3 visits. Results: 89 participants (24 males/65 females; mean age: 55.0 ± 14.2 years) were included: 20 presented moderate DED symptoms and 69 severe DED symptoms. Significant differences were found for the spherocylindrical refraction (vector analysis) between visit 1 and visits 2 and 3. Following cumulative analysis, 11.86 % and 16.94 % of participants had more than 0.5 dioptre (D) change in mean keratometry and keratometric astigmatism, respectively, at 3 months post-treatment. A total of 5.40 % had a sphere and cylinder change greater than 0.50D and 16.21 % had the axis changed more than 10 degrees (vector analysis). These changes were particularly significant in patients with severe DED symptoms. Conclusions: Keratometry readings and refraction can change following thermo-mechanical skin treatment for DED, especially in those patients with severe DED symptoms. This should be considered as potential errors in intraocular lens calculations may be induced.Citation
Blanco-Vázquez M, Gil-Cazorla R, Barua A, Taneja M, Hanneken L, Shah S. Impact of thermo-mechanical skin treatment on refraction and keratometry in patients with dry eye disease and the implications for cataract surgery. Cont Lens Anterior Eye. 2024 Apr 8:102164. doi: 10.1016/j.clae.2024.102164Type
ArticlePMID
38594154Journal
Contact Lens & Anterior EyePublisher
Elsevierae974a485f413a2113503eed53cd6c53
10.1016/j.clae.2024.102164