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    Completion of annual diabetes care processes and mortality: a cohort study using the National Diabetes Audit for England and Wales.

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    Author
    Holman, Naomi
    Knighton, Peter
    OʼKeefe, Jackie
    Wild, Sarah H
    Brewster, Sarah
    Price, Hermione
    Patel, Kiran
    Hanif, Wasim
    Patel, Vinod
    Gregg, Edward W
    Holt, Richard I G
    Gadsby, Roger
    Khunti, Kamlesh
    Valabhji, Jonathan
    Young, Bob
    Sattar, Naveed
    Show allShow less
    Publication date
    2021-09-01
    Subject
    Cardiology
    Public health. Health statistics. Occupational health. Health education
    
    Metadata
    Show full item record
    Abstract
    Aim: To conduct an analysis to assess whether the completion of recommended diabetes care processes (glycated haemoglobin [HbA1c], creatinine, cholesterol, blood pressure, body mass index [BMI], smoking habit, urinary albumin, retinal and foot examinations) at least annually is associated with mortality. Materials and methods: A cohort from the National Diabetes Audit of England and Wales comprising 179 105 people with type 1 and 1 397 790 people with type 2 diabetes, aged 17 to 99 years on January 1, 2009, diagnosed before January 1, 2009 and alive on April 1, 2013 was followed to December 31, 2019. Cox proportional hazards models adjusting for demographic characteristics, smoking, HbA1c, blood pressure, serum cholesterol, BMI, duration of diagnosis, estimated glomerular filtration rate, prior myocardial infarction, stroke, heart failure, respiratory disease and cancer, were used to investigate whether care processes recorded January 1, 2009 to March 31, 2010 were associated with subsequent mortality. Results: Over a mean follow-up of 7.5 and 7.0 years there were 26 915 and 388 093 deaths in people with type 1 and type 2 diabetes, respectively. Completion of five or fewer, compared to eight, care processes (retinal screening not included as data were not reliable) had a mortality hazard ratio (HR) of 1.37 (95% confidence interval [CI] 1.28-1.46) in people with type 1 and 1.32 (95% CI 1.30-1.35) in people with type 2 diabetes. The HR was higher for respiratory disease deaths and lower in South Asian ethnic groups. Conclusions: People with diabetes who have fewer routine care processes have higher mortality. Further research is required into whether different approaches to care might improve outcomes for this high-risk group.
    Citation
    Holman N, Knighton P, OʼKeefe J, Wild SH, Brewster S, Price H, Patel K, Hanif W, Patel V, Gregg EW, Holt RIG, Gadsby R, Khunti K, Valabhji J, Young B, Sattar N. Completion of annual diabetes care processes and mortality: A cohort study using the National Diabetes Audit for England and Wales. Diabetes Obes Metab. 2021 Dec;23(12):2728-2740. doi: 10.1111/dom.14528. Epub 2021 Sep 1
    Type
    Article
    Other
    Handle
    http://hdl.handle.net/20.500.14200/5009
    Additional Links
    http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1463-1326
    DOI
    10.1111/dom.14528
    PMID
    34405512
    Journal
    Diabetes, Obesity and Metabolism
    Publisher
    Wiley-Blackwell
    ae974a485f413a2113503eed53cd6c53
    10.1111/dom.14528
    Scopus Count
    Collections
    Diabetes and Endocrinology
    Diabetes and Endocrinology

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