Remote monitoring of atrial fibrillation recurrence using mHealth technology (REMOTE-AF).
Author
Adasuriya, GamithBarsky, Andrey
Kralj-Hans, Ines
Mohan, Siddhartha
Gill, Simrat
Chen, Zhong
Jarman, Julian
Jones, David
Valli, Haseeb
Gkoutos, Georgios V
Markides, Vias
Hussain, Wajid
Wong, Tom
Kotecha, Dipak
Haldar, Shouvik
Publication date
2024-02-12Subject
Cardiology
Metadata
Show full item recordAbstract
REMOTE-AF (NCT05037136) was a prospectively designed sub-study of the CASA-AF randomized controlled trial (NCT04280042). Participants without a permanent pacemaker had an ILR implanted at their index ablation procedure for longstanding persistent AF. Heart rate and step count were continuously monitored using photoplethysmography (PPG) from a commercially available wrist-worn wearable. Photoplethysmography-recorded HR data were pre-processed with noise filtration and episodes at 1-min interval over 30 min of HR elevations (Z-score = 2) were compared with corresponding ILR data. Thirty-five patients were enrolled, with mean age 70.3 ± 6.8 years and median follow-up 10 months (interquartile range 8-12 months). Implantable loop recorder analysis revealed 17 out of 35 patients (49%) had recurrence of AF/AT. Compared with ILR recurrence, wearable-derived elevations in HR ≥ 110 beats per minute had a sensitivity of 95.3%, specificity 54.1%, positive predictive value (PPV) 15.8%, negative predictive value (NPV) 99.2%, and overall accuracy 57.4%. With PPG-recorded HR elevation spikes (non-exercise related), the sensitivity was 87.5%, specificity 62.2%, PPV 39.2%, NPV 92.3%, and overall accuracy 64.0% in the entire patient cohort. In the AF/AT recurrence only group, sensitivity was 87.6%, specificity 68.3%, PPV 53.6%, NPV 93.0%, and overall accuracy 75.0%.Citation
Adasuriya G, Barsky A, Kralj-Hans I, Mohan S, Gill S, Chen Z, Jarman J, Jones D, Valli H, Gkoutos GV, Markides V, Hussain W, Wong T, Kotecha D, Haldar S. Remote monitoring of atrial fibrillation recurrence using mHealth technology (REMOTE-AF). Eur Heart J Digit Health. 2024 Feb 12;5(3):344-355. doi: 10.1093/ehjdh/ztae011.Type
ArticleAdditional Links
https://www.ncbi.nlm.nih.gov/pmc/journals/4338/PMID
38774381Publisher
Oxford University Pressae974a485f413a2113503eed53cd6c53
10.1093/ehjdh/ztae011