Diagnostic Accuracy of FEC-PET/CT, FDG-PET/CT, and Diffusion-Weighted MRI in Detection of Nodal Metastases in Surgically Treated Endometrial and Cervical Carcinoma.

Rockall, Andrea G; Barwick, Tara D; Wilson, William; Singh, Naveena; Bharwani, Nishat; Sohaib, Aslam; Nobbenhuis, Marielle; Warbey, Victoria; Miquel, Marc; Koh, Dow-Mu; De Paepe, Katja N; Martin-Hirsch, Pierre; Ghaem-Maghami, Sadaf; Fotopoulou, Christina; Stringfellow, Helen; Sundar, Sudha; Manchanda, Ranjit; Sahdev, Anju; Hackshaw, Allan; Cook, Gary J

Affiliation

Imperial College London; Imperial College Healthcare NHS Trust; Barts Health NHS Trust; Sandwell and West Birmingham NHS Trust

Publication date

2021-09-15

Subject

Gynaecology
Oncology. Pathology.

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Abstract

Preoperative nodal staging is important for planning treatment in cervical cancer and endometrial cancer, but remains challenging. We compare nodal staging accuracy of 18F-ethyl-choline-(FEC)-PET/CT, 18F-fluoro-deoxy-glucose-(FDG)-PET/CT, and diffusion-weighted-MRI (DW-MRI) with conventional morphologic MRI.

Citation

Rockall AG, Barwick TD, Wilson W, Singh N, Bharwani N, Sohaib A, Nobbenhuis M, Warbey V, Miquel M, Koh DM, De Paepe KN, Martin-Hirsch P, Ghaem-Maghami S, Fotopoulou C, Stringfellow H, Sundar S, Manchanda R, Sahdev A, Hackshaw A, Cook GJ; MAPPING Study Group. Diagnostic Accuracy of FEC-PET/CT, FDG-PET/CT, and Diffusion-Weighted MRI in Detection of Nodal Metastases in Surgically Treated Endometrial and Cervical Carcinoma. Clin Cancer Res. 2021 Dec 1;27(23):6457-6466.

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Article
Other