One-step nucleic acid amplification : CK 19 copy number as a predictor of further axillary involvement

Tafazal, Habib; Atherton, Gavin; Amin, Verda; Dakka, Mahmoud; Park, Michael; Smith, Adrian; Harries, Simon; Jones, Lucie; Clarke, Dayalan

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Author

Tafazal, Habib
Atherton, Gavin
Amin, Verda
Dakka, Mahmoud
Park, Michael
Smith, Adrian
Harries, Simon
Jones, Lucie
Clarke, Dayalan

Affiliation

South Warwickshire University NHS Foundation Trust

Publication date

2015-06

Subject

Oncology. Pathology.
Surgery

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Abstract

Introduction: In 2013, the National Institute of Clinical Excellence (NICE) endorsed the use of One step nucleic acid amplification (OSNA) in clinical practice. Our study aims to seek a correlation between the OSNA results, indicated by CK 19 mRNA copy numbers and the likelihood of non-sentinel axillary involvement in patients with macro-metastases.

Citation

Tafazal H, Atherton G, Amin V, Dakka M, Park M, Smith A, Harries S, Jones L, Clarke D. P098. One-step nucleic acid amplification: CK 19 copy number as a predictor of further axillary involvement. Eur J Surg Oncol. 2015 Jun;41(6):S54. doi: 10.1016/j.ejso.2015.03.136.

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Conference Output