Goel, AimeeKulkarni, GirishCotici, AlexandruPaluzzi, AlessandroHayton, TomChelvarajah, Ramesh2023-07-032023-07-032023-05-05Goel A, Kulkarni G, Cotici A, Paluzzi A, Hayton T, Chelvarajah R. Volume maximised glycerol rhizolysis for trigeminal neuralgia: a single centre analysis of outcomes. Br J Neurosurg. 2025 Apr;39(2):191-196. doi: 10.1080/02688697.2023.2207657. Epub 2023 May 5.1360-046X10.1080/02688697.2023.220765737144252http://hdl.handle.net/20.500.14200/114537 procedures were carried out for typical trigeminal neuralgia, 13 for secondary trigeminal neuralgia, and 3 for atypical trigeminal neuralgia. Overall, pain freedom was achieved in 85% cases, and 92% in patients with typical trigeminal neuralgia. Median duration of pain freedom in patients with typical trigeminal neuralgia was 63 months, versus 6 months in those with secondary trigeminal neuralgia (p < 0.00001). 14 procedures (26.4%) resulted in mild and temporary complications. 54.7% of cases experienced hypoaesthesia in a distribution similar to or less extensive than the distribution of trigeminal neuralgia. The presence of hypoaesthesia post-procedure was highly predictive of longer pain freedom (95 months versus 8 months median pain freedom (p = 0.00003)).enNeurologyArticle