AlShammari, AbdullahPatel, AkshayBoyle, MarkProli, ChiaraGallesio, Jose AlvarezWali, AnujDe Sousa, PauloLim, Eric2024-12-062024-12-062024-11-05AlShammari A, Patel A, Boyle M, Proli C, Gallesio JA, Wali A, De Sousa P, Lim E. Prevalence of invasive lung cancer in pure ground glass nodules less than 30 mm: A systematic review. Eur J Cancer. 2024 Dec;213:115116. doi: 10.1016/j.ejca.2024.115116. Epub 2024 Nov 5.1879-085210.1016/j.ejca.2024.11511639546859http://hdl.handle.net/20.500.14200/6693All published studies were retrospective (n = 28) and the majority conducted in Asia (n = 25). Baseline patient cohorts were mainly from published surgical series (n = 22) or lung cancer screening programs (n = 6). The proportion of minimally invasive and invasive cancer ranged from 0.9 % to 100 % with a pooled prevalence of 42.4 % [95 % CI: 0.28, 0.57]. Considerable heterogeneity was observed (I2 =99 %) and patient selection was the most significant contribution, accounting for 73 % of the observed heterogeneity (p < 0.0001). Meta-regression based on size selection and country of investigation revealed no significant contribution to effect size effect or heterogeneity.enCopyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.Oncology. Pathology.Respiratory medicineRadiologyPublic health. Health statistics. Occupational health. Health educationSurgeryArticleEuropean journal of cancer (Oxford, England : 1990)